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	<title>sedatives Archives - Filter</title>
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		<title>Do Any Other Meth Users Find These Labels Pretty Arbitrary?</title>
		<link>/meth-fentanyl-overdose-death-data/</link>
		
		<dc:creator><![CDATA[Kastalia Medrano]]></dc:creator>
		<pubDate>Wed, 05 Jul 2023 18:51:21 +0000</pubDate>
				<category><![CDATA[FilterMag]]></category>
		<category><![CDATA[Use + Harm Reduction]]></category>
		<category><![CDATA[methamphetamine]]></category>
		<category><![CDATA[sedatives]]></category>
		<category><![CDATA[stimulants]]></category>
		<guid isPermaLink="false">/?p=16838</guid>

					<description><![CDATA[<p>If any of you use stimulants and have a particularly good system for waking up on time, I wouldn’t mind ...</p>
<p>The post <a href="/meth-fentanyl-overdose-death-data/">Do Any Other Meth Users Find These Labels Pretty Arbitrary?</a> appeared first on <a href="/">Filter</a>.</p>
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										<content:encoded><![CDATA[<p><span class="wpsdc-drop-cap">I</span>f any of you use stimulants and have a particularly good system for waking up on time, I wouldn’t mind hearing about it, because mine is getting more and more elaborate without working any better.</p>
<p><span style="font-weight: 400;">I still set multiple alarms on my phone, but because these are not to be trusted I also have an analog alarm clock that makes a sound I viscerally hate. The alarm clock is at least 5 feet away, and on top of it is at least one <a href="/booty-bumping-harm-reduction/">boofing syringe</a> I&#8217;ve filled with somewhere around .1 grams meth the night before. </span><span style="font-weight: 400;">There are two more next to my bed; I need the alarm clock to be out of arm&#8217;s reach so I have to get up to make it stop, but I need enough meth to be within arm&#8217;s reach to be able to do this.</span></p>
<p><span style="font-weight: 400;">Over the past six months I have gradually trained the cat, kind of, to yell at me for breakfast around 6 am rather than 4:45 am. This is not a foolproof system either, so there&#8217;s usually another pre-loaded syringe in the bathroom in case I forget to use enough of the bedside ones. Sometimes a few scattered around in places like the fridge, for reasons that aren&#8217;t entirely clear to me.</span></p>
<blockquote><p>Stimulants and sedatives are what separate daytime and nighttime, more so than the position of the sun.</p></blockquote>
<p>Stimulants have been how I start my day almost every day for the past decade. But sedatives determine whether my day starts in the morning, and whether it&#8217;s one with 24 hours or one that&#8217;s going to surprise me.</p>
<p>If the day is the 24-hour kind, I&#8217;ll <a href="/booty-bumping-meth/">boof</a> somewhere around half a gram of meth from between when I wake up and when I switch to nighttime drugs. There&#8217;s a rotating cast of a dozen licit and illicit substances, not all of which are technically sedatives, but one way or another help me go to sleep. They get stacked on top of each other in whatever combinations make sense, sort of the way opioid agonist medications are <a href="/canada-safe-supply-kadian/">prescribed in Canada</a>. Usually two at a time, but sometimes three, based more on availability than preference.</p>
<p>Often I start using them at an hour that would be considered bedtime, but it can also be 5 am or 5 pm or not at all. <span style="font-weight: 400;">Stimulants and sedatives are what separate daytime and nighttime, more so than the position of the sun. If I’ve switched from uppers to downers, the day is over.</span></p>
<p><a href="/meth-overamp/">My meth use</a> would fall under &#8220;addiction&#8221; for people who use the term, &#8220;substance use disorder&#8221; to the non-substance users in harm reduction, probably &#8220;chronic substance use/abuse&#8221; to medical professionals, &#8220;self-medication&#8221; to anyone else not sure what to call it and &#8220;off-label medical use for treatment-resistant depression&#8221; whenever I <a href="/adderall-shortage-meth/">switch from meth to Adderall</a>. It&#8217;s also &#8220;chaotic/problematic use&#8221; depending on how you squint at it, and &#8220;recreational use&#8221; because meth is fun.</p>
<blockquote><p>I don&#8217;t think of myself as a polysubstance user, but it&#8217;s what the overdose data would call me if I died.</p></blockquote>
<p>People are hard to put neatly into categories, but data is easy. A few years ago we began to characterize the overdose crisis as having evolved past the point of being opioid-specific; we&#8217;re in a <a href="https://www.cdc.gov/mmwr/volumes/68/wr/mm6817a3.htm">polysubstance use crisis</a> now, a fourth wave marked by stimulants and especially meth. I don&#8217;t think of myself as a polysubstance user, because it&#8217;s not really a term people use in real life, but it&#8217;s <a href="/meth-overdose-death-data/">what the overdose data would call me if I died</a>.</p>
<p>When <a href="/meth-overdose-death-data/">post-mortem toxicology</a> reveals both fentanyl and meth, the next thing we say is that we don&#8217;t know whether they were meth users whose supply was adulterated with fent, or polysubstance users who mixed meth and fent intentionally. I have no idea why this matters. The opioid supply is also adulterated with fent, even for people who prefer it to heroin. No one got to choose—in the cases where people intended to consume fent, they probably didn&#8217;t intend to die.</p>
<p>Everyone&#8217;s a polysubstance user if you base that off a single moment in time, which is all death data ever does. Many meth users, including myself, don&#8217;t think of themselves as fent users but do use it sometimes. In my case, access to drug-checking allows me to go about it in a way I feel more or less comfortable with, which has been handy. It&#8217;s the downer that&#8217;s always available.</p>
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<p>&nbsp;</p>
<p><em>Photograph courtesy of Kastalia Medrano</em></p>
<p><a class="a2a_button_facebook" href="https://www.addtoany.com/add_to/facebook?linkurl=%2Fmeth-fentanyl-overdose-death-data%2F&linkname=Do%20Any%20Other%20Meth%20Users%20Find%20These%20Labels%20Pretty%20Arbitrary%3F" title="Facebook" rel="nofollow noopener" target="_blank"></a><a class="a2a_button_twitter" href="https://www.addtoany.com/add_to/twitter?linkurl=%2Fmeth-fentanyl-overdose-death-data%2F&linkname=Do%20Any%20Other%20Meth%20Users%20Find%20These%20Labels%20Pretty%20Arbitrary%3F" title="Twitter" rel="nofollow noopener" target="_blank"></a><a class="a2a_button_email" href="https://www.addtoany.com/add_to/email?linkurl=%2Fmeth-fentanyl-overdose-death-data%2F&linkname=Do%20Any%20Other%20Meth%20Users%20Find%20These%20Labels%20Pretty%20Arbitrary%3F" title="Email" rel="nofollow noopener" target="_blank"></a></p><p>The post <a href="/meth-fentanyl-overdose-death-data/">Do Any Other Meth Users Find These Labels Pretty Arbitrary?</a> appeared first on <a href="/">Filter</a>.</p>
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		<title>“Tranq Dope”—The Heroin Combo That’s Been Putting Philly to Sleep</title>
		<link>/tranq-dope-the-heroin-combo-thats-been-putting-philly-to-sleep/</link>
		
		<dc:creator><![CDATA[Christopher Moraff]]></dc:creator>
		<pubDate>Tue, 02 Apr 2019 14:16:39 +0000</pubDate>
				<category><![CDATA[Use + Harm Reduction]]></category>
		<category><![CDATA[heroin]]></category>
		<category><![CDATA[sedatives]]></category>
		<guid isPermaLink="false">/?p=6381</guid>

					<description><![CDATA[<p>Last May, as physicians, drug users and harm reduction workers grappled with a new and perplexing arrival in Philadelphia’s rapidly ...</p>
<p>The post <a href="/tranq-dope-the-heroin-combo-thats-been-putting-philly-to-sleep/">“Tranq Dope”—The Heroin Combo That’s Been Putting Philly to Sleep</a> appeared first on <a href="/">Filter</a>.</p>
]]></description>
										<content:encoded><![CDATA[<p><span class="wpsdc-drop-cap">L</span>ast May, as physicians, drug users and harm reduction workers grappled with a new and perplexing arrival in Philadelphia’s <a href="/2019/01/22/why-crystal-meth-has-made-a-big-comeback-in-philadelphia/"><span style="font-weight: 400;">rapidly evolving</span></a><span style="font-weight: 400;"> open-air drug markets—bags of heroin and/or fentanyl contaminated with the powerful synthetic cannabinoid 5F-ADB, known as “K2”—I received an early morning call from a regular source in Kensington’s drug-user community.</span></p>
<p><span style="font-weight: 400;">“I have something for ya you’re really gonna like,” he said excitedly. “When can we meet? I’ve been carrying it all night.”</span></p>
<p><span style="font-weight: 400;">I had no idea what “it” was. But by then I was getting pretty well known as “</span><a href="/2018/12/13/what-i-found-when-i-applied-hundreds-of-fentanyl-tests-to-phillys-street-drugs/"><span style="font-weight: 400;">that journalist who tests drugs and posts the results</span></a><span style="font-weight: 400;">.” So I was accustomed to people giving me small samples of their drugs to test.</span></p>
<p><span style="font-weight: 400;">After the first outbreak of street dope contaminated with synthetic cannabinoids, which </span><a href="/2018/09/25/over-200-philly-heroin-users-poisoned-over-the-weekend-potentially-due-to-synthetic-cannabinoid-contamination/"><span style="font-weight: 400;">sickened nearly 200 people</span></a><span style="font-weight: 400;"> in September last year, people were literally handing me full bags (sometimes several) of drugs they wanted nothing to do with.</span></p>
<p><span style="font-weight: 400;">But I was not expecting what my source brought me that humid day last May. Reaching into his duffle bag, he produced a gallon ziplock bag containing eight empty bottles that had contained xylazine—a non-opioid tranquilizer used to sedate large animals. Referred to locally as “sleep cut,” xylazine has been used as a cutting agent for heroin for some time in cities like Philadelphia and New York.</span></p>
<p><span style="font-weight: 400;"><img decoding="async" class="img-responsive alignnone wp-image-6383" src="/wp-content/uploads/2019/04/Screenshot-2019-04-02-at-10.19.14-262x300.png" alt="" width="812" height="926" />It is currently not scheduled in the US. Obtaining the drug requires only a veterinarian prescription, which is a piece of cake if you own a few horses, know someone who does, or just know which palms to grease. The bottles I obtained from my source were from two different providers—both veterinary labs located in the Midwest that sell a variety of items for the equine community. (Here is a </span><a href="http://www.akorn.com/documents/catalog/sell_sheets/59399-111-50.pdf"><span style="font-weight: 400;">fact sheet</span></a><span style="font-weight: 400;"> on the drug from one of the labs it was sourced; to be clear, the distributor would have no way of knowing how the product was being put to use).</span></p>
<p><span style="font-weight: 400;">Xylazine is approved by the FDA for animal use only. That’s because it’s known to be harmful in humans. Clinical findings reported that xylazine users presented limb skin lesions, ulcerations and greater physiological deterioration than users of heroin only. Deaths where the drug is named are rare, however. A 2012 paper </span><a href="https://www.ncbi.nlm.nih.gov/pubmed/24769343"><span style="font-weight: 400;">attributed just 22 deaths </span></a><span style="font-weight: 400;">to xylazine; recently, a suburban Philadelphia paper included a rare mention of xylazine death in February, when it </span><a href="https://www.dailylocal.com/news/local/chesco-coroner-s-office-identifies-new-deadly-drug-from-overdose/article_e8e4fafc-2bc9-11e9-b2e6-f330b4d86d22.html"><span style="font-weight: 400;">attributed two overdoses</span></a><span style="font-weight: 400;"> to the “new” drug. (The victims also had fentanyl and acetyl fentanyl in their system, which suggests to me it’s not xylazine that’s new, but more likely <em>testing</em> for it by the county lab).</span></p>
<p><span style="font-weight: 400;">Recreational human use of xylazine</span><span style="font-weight: 400;">—</span><span style="font-weight: 400;">both by itself and mixed with heroin and/or cocaine</span><span style="font-weight: 400;">—reportedly </span><span style="font-weight: 400;">first emerged in Puerto Rico, where xylazine has been described as the “</span><a href="https://www.huffpost.com/entry/puerto-rico-drug-addiction_n_2411317"><span style="font-weight: 400;">zombie</span></a><span style="font-weight: 400;"> drug” by the media due to its heavy sedating effect. This short documentary from </span><a href="https://video.nationalgeographic.com/tv/drugs-inc/00000144-16ca-dcf1-a954-57db6b6c0000"><i><span style="font-weight: 400;">National Geographic</span></i></a><span style="font-weight: 400;"> illustrates the drug’s pervasiveness n Puerto Rico and its effects.</span></p>
<p><span style="font-weight: 400;">One American former heroin user I spoke with lived in Puerto Rico when she began using drugs. She told </span><i><span style="font-weight: 400;">Filter</span></i><span style="font-weight: 400;"> that she remembers traveling to a Midwest state (where “tar” heroin would have been all that was available at the time) and thinking “there’s something wrong with the dope here.” She’d become so accustomed to “tranq dope” that it changed her perception of what heroin </span><i><span style="font-weight: 400;">should</span></i><span style="font-weight: 400;"> feel like.</span></p>
<p><span style="font-weight: 400;">That said, not everyone likes the combination. </span><span style="font-weight: 400;">The tranq dope that xylazine produces in combination with heroin is favored by some, and disdained by others. Louis, a Philadelphia Latino in his mid-30s, told </span><i><span style="font-weight: 400;">Filter</span></i><span style="font-weight: 400;"> that he prefers the energy he gets from pure opioids, but that he knows people who prefer the added sedation of tranquilizer cut.</span></p>
<blockquote><p><span style="font-weight: 400;">Asked how she avoids it, she said she depends on word of mouth, or else buys several different heroin brands to diversify her personal supply.</span></p></blockquote>
<p><span style="font-weight: 400;">“I hate it” said Jess, a heroin user I met in Kensington on April 1, when asked about tranq dope. Jess has a full-time job with a major retail outlet, but said she has trouble working when using tranq dope, due to its sedating effect. </span></p>
<p><span style="font-weight: 400;">Asked how she avoids it, she said she depends on word of mouth, or else buys several different heroin brands to diversify her personal supply. This is a tactic employed by more IV drug users these days, as market <a href="/2018/11/20/el-chapos-trial-solves-nothing-the-freelancer-effect-applies-wherever-you-look/">disruption</a> has all but eliminated any expectation of consistency in product supply. Some would rather risk arrest traveling to different drug-dealing “sets” than risk spending all their money on one brand.</span></p>
<p><span style="font-weight: 400;">Others deliberately obtain a bag or two of tranq dope for their “bedtime” shot, believing it more likely to hold them through the night. </span></p>
<p><span style="font-weight: 400;">But like many other substances mixed into illicit-market supplies, xylazine is often unavoidable, whether people wish to take it or not.</span></p>
<p><span style="font-weight: 400;">Other examples of this happening crop up all the time. For instance, “speedball” use spiked throughout 2017 in Philly as well as much of the Northeast and as far west as Ohio</span><span style="font-weight: 400;">—</span><span style="font-weight: 400;">yet many injection drug users I spoke with last year were convinced that the $5 bags of white injectable powder being sold as cocaine were instead “bath salts,” a generic name used to describe dozens of popular “substituted cathinones”—a class of mild-to-potent synthetic stimulants. When I started carrying around cocaine test strips I surprised more than a few: Every single bag of suspected cocaine that I tested came back positive for the drug (which of course doesn’t rule out the possibility it was cut with some other stimulant as well). </span></p>
<p><span style="font-weight: 400;">That situation continues, with coke quality picking up, according to my sources. The DEA says that record coca production in Colombia has actually created a surplus of cocaine in Philadelphia, and on March 20, US Customs agents at the Port of Philadelphia logged their biggest seizure of the drug in two decades—netting nearly 1,200 pounds of coke bricks hidden in a shipping container.</span></p>
<blockquote><p><span style="font-weight: 400;">More than a dozen people stood bent over or else lay splayed out on the sidewalk; all were in a state of total or almost total unconsciousness.</span></p></blockquote>
<p><span style="font-weight: 400;">Several weeks after receiving the largest single piece of physical evidence anyone I spoke to had seen confirming the presence of xylazine in the Philly heroin supply, I was reminded why the medicine is called the “zombie drug.”</span></p>
<p><span style="font-weight: 400;">I learned through word of mouth that a new dope sample had just hit the street that was loaded with the sedative.</span></p>
<p><span style="font-weight: 400;">“Look around,” a middle-aged heroin user in a wheelchair told me near the major intersection of Kensington and Allegheny Avenues just after sundown. “You can tell who got one, right?” He laughed as we scanned the horizon. More than a dozen people stood bent over or else lay splayed out on the sidewalk; all were in a state of total or almost total unconsciousness.</span></p>
<blockquote><p><span style="font-weight: 400;">“Like any street drug, I always recommend heating up your cooker to kill off any bacteria and to help break down any impurities.”</span></p></blockquote>
<p><span style="font-weight: 400;">In all my time covering the heroin trade I had never previously seen it. My source said he found the bottles discarded by the roadside along with two paper “Mannite” wrappers. “Mannite” (Mannitol) is a type of alcohol sugar and is one of the most common cutting agents for heroin;  it’s about half as sweet as lactose, dissolves easily, and can be toasted lightly in an oven producing the tan color that IV drug users often claim (erroneously) proves the drug in the cooker is heroin (as opposed to fentanyl, which they say dissolves clear).</span></p>
<p><span style="font-weight: 400;"><img loading="lazy" decoding="async" class="img-responsive alignnone wp-image-6385" src="/wp-content/uploads/2019/04/Screenshot-2019-04-02-at-10.18.19-300x264.png" alt="" width="808" height="711" srcset="/wp-content/uploads/2019/04/Screenshot-2019-04-02-at-10.18.19-300x264.png 300w, /wp-content/uploads/2019/04/Screenshot-2019-04-02-at-10.18.19-376x331.png 376w, /wp-content/uploads/2019/04/Screenshot-2019-04-02-at-10.18.19.png 609w" sizes="auto, (max-width: 808px) 100vw, 808px" />Unlike with other commonly used intravenous drugs and cutting agents, there is no easy way to test for the presence of xylazine. This presents a problem for harm reduction workers.</span></p>
<p><span style="font-weight: 400;">“Xylazine, commonly known as ‘tranq’, and other animal tranquilizers, obviously were not manufactured for the intent for human consumption. Therefore, there may inherently be some forms of bacteria or fungi that are bodies are not equipped to fight.” said Shawn Westfahl, a long-time harm reduction service provider and advocate in Philadelphia, who says he frequently encounters IV drug users with the skin lesions commonly associated with xylazine use.</span></p>
<p><span style="font-weight: 400;">So Westfahl, whose work includes giving overdose reversal trainings, defers to standard harm reduction practices when asked how he has been dealing with the spike in tranq dope.</span></p>
<p><span style="font-weight: 400;">“Like any street drug, I always recommend heating up your cooker to kill off any bacteria and to help break down any impurities,” he told </span><i><span style="font-weight: 400;">Filter</span></i><span style="font-weight: 400;">. “And as with any suspected overdose, administer naloxone and always support the person’s breathing by giving them rescue breaths if they are not breathing, or by rolling them into the recovery position if they are.” </span></p>
<p><span style="font-weight: 400;">Xylazine may be less dangerous than some other common heroin adulterants, but it still poses real risks. And its widespread presence in Philly and beyond is yet another illustration of the inherent instability and riskiness of unregulated drug markets.</span></p>
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<p>Correction, April 18, 2023: <em>A previous version of this article included a calculation that mischaracterized xylazine dosing.</em></p>
<p><em>All photos by Christopher Moraff</em></p>
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